Andréa C LeBlanc Selected Research

Caspase 6

1/2022	Therapeutic potential of Nlrp1 inflammasome, Caspase-1, or Caspase-6 against Alzheimer disease cognitive impairment.
1/2021	Caspase-6-cleaved Tau fails to induce Tau hyperphosphorylation and aggregation, neurodegeneration, glial inflammation, and cognitive deficits.
1/2018	Differential susceptibility of striatal, hippocampal and cortical neurons to Caspase-6.
1/2014	Inflammation-induced tumorigenesis in mouse colon is caspase-6 independent.
1/2013	Expression and activation of caspase-6 in human fetal and adult tissues.
12/2009	Caspase-6 activation in familial alzheimer disease brains carrying amyloid precursor protein or presenilin i or presenilin II mutations.
3/2009	Self-activation of Caspase-6 in vitro and in vivo: Caspase-6 activation does not induce cell death in HEK293T cells.
4/2007	Activation of caspase-6 in aging and mild cognitive impairment.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Andréa C LeBlanc Research Topics

Disease

11	Alzheimer Disease (Alzheimer's Disease) 01/2022 - 04/2007
6	Cognitive Dysfunction 01/2022 - 04/2007
5	Breast Neoplasms (Breast Cancer) 01/2017 - 12/2006
3	Inflammation (Inflammations) 11/2020 - 01/2014
3	Prion Diseases (Transmissible Spongiform Encephalopathies) 01/2017 - 01/2004
2	Encephalitis (Encephalitis, Rasmussen) 11/2020 - 01/2018
2	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2018 - 07/2013
2	Neoplasms (Cancer) 01/2014 - 02/2009
2	Amyloid Plaque 12/2009 - 04/2007
2	Creutzfeldt-Jakob Syndrome (Creutzfeldt-Jakob Disease) 08/2009 - 05/2007
1	Huntington Disease (Huntington's Disease) 01/2018
1	Memory Disorders (Memory Loss) 01/2018
1	Carcinogenesis 01/2014
1	Colonic Neoplasms (Colon Cancer) 01/2014
1	Stomach Neoplasms (Stomach Cancer) 03/2013
1	Nonaka type Distal myopathy 08/2009
1	Fatal Familial Insomnia 05/2007

Drug/Important Bio-Agent (IBA)

8	Caspase 6IBA 01/2022 - 04/2007
8	Prion ProteinsIBA 01/2017 - 01/2004
6	Proteins (Proteins, Gene)FDA Link 01/2022 - 04/2007
3	Amyloid beta-PeptidesIBA 11/2020 - 04/2007
3	Brefeldin AIBA 01/2017 - 03/2013
2	interleukin-1beta-converting enzyme inhibitorIBA 04/2021 - 11/2020
2	belnacasanIBA 11/2020 - 01/2018
2	Pharmaceutical PreparationsIBA 11/2020 - 01/2017
2	Messenger RNA (mRNA)IBA 01/2014 - 03/2013
2	TunicamycinIBA 07/2013 - 03/2013
2	ThapsigarginIBA 07/2013 - 03/2013
2	CaspasesIBA 01/2013 - 03/2009
1	Leucine (L-Leucine)FDA Link 01/2022
1	InflammasomesIBA 01/2022
1	NucleotidesIBA 01/2022
1	Amino Acids FDA Link 01/2021
1	Genetic Markers (Genetic Marker)IBA 11/2020
1	Biomarkers (Surrogate Marker)IBA 12/2019
1	SynaptophysinIBA 01/2018
1	Dextran SulfateIBA 01/2014
1	AzoxymethaneIBA 01/2014
1	Carrier Proteins (Binding Protein)IBA 03/2013
1	Immunoglobulin Heavy Chains (Immunoglobulin Heavy Chain)IBA 03/2013
1	Proteasome Endopeptidase Complex (Proteasome)IBA 04/2010
1	Valosin Containing ProteinIBA 04/2010
1	UbiquitinIBA 04/2010
1	PresenilinsIBA 12/2009
1	Amyloid (Amyloid Fibrils)IBA 12/2009
1	ChromatinIBA 08/2009
1	Adenosine Triphosphatases (ATPase)IBA 08/2009
1	ElementsIBA 02/2009